BACLOFEN (INJ) (TAB) AND DESCRIPTION:
Baclofen is a muscle relaxant and antispastic agent that is primarily used to treat muscle spasticity caused by conditions like:
Multiple sclerosis (MS)
Spinal cord injuries or diseases
Occasionally, cerebral palsy or stroke-related spasticity
🔹 Basic Description:
Generic name: Baclofen
Common brand names: Lioresal, Gablofen (injection form)
🔹 Mechanism of Action:
Baclofen works by activating GABA-B receptors in the spinal cord. This reduces the transmission of nerve signals that cause muscle tightness and spasms, helping muscles relax.
🔹 Forms Available:
Oral tablets (most common)
Oral liquid
Intrathecal injection (directly into spinal fluid, for severe spasticity)
🔹 Common Side Effects:
Drowsiness
Dizziness
Weakness
Fatigue
Nausea
Caution: Sudden discontinuation can lead to withdrawal symptoms like hallucinations, seizures, and rebound spasticity.
🔹 Precautions:
Use with care in patients with kidney disease.
Avoid alcohol or CNS depressants (increased sedation).
Not usually recommended during pregnancy unless clearly needed.
BACLOFEN (INJ)
Here is information about Baclofen Injection in both English and Urdu:
🧪 Baclofen Injection – English
Generic Name: Baclofen
Form: Injection
Route: Intrathecal (injected into spinal fluid)
Uses:
Treats severe muscle spasms
Commonly used in conditions like multiple sclerosis, spinal cord injuries, or cerebral palsy
Mechanism:
Baclofen acts on the spinal cord nerves to reduce muscle tightness and spasticity.
Dosage:
Given by a doctor via an intrathecal pump or injection directly into the spinal canal.
Side Effects:
Drowsiness
Weakness
Dizziness
Nausea
Low blood pressure
Warnings:
Do not stop suddenly – may cause seizures or hallucinations
Use under medical supervision only
💉 Baclofen Injection – اردو میں
دوائی کا نام: Baclofen
شکل: انجکشن
طریقہ استعمال: ریڑھ کی ہڈی کے پانی میں (Intrathecal)
استعمالات:
شدید پٹھوں کے کھچاؤ (Muscle Spasm) کے علاج کے لیے
خاص طور پر ملٹی پل سکلیروسیز, ریڑھ کی ہڈی کی چوٹیں یا دماغی فالج (Cerebral Palsy) میں
کام کرنے کا طریقہ:
یہ ریڑھ کی ہڈی کے اعصاب پر اثر انداز ہو کر پٹھوں کی سختی کو کم کرتا ہے۔
خوراک:
صرف ڈاکٹر کے ذریعے اسپائنل فلوئیڈ میں دیا جاتا ہے (پمپ یا انجکشن سے)
مضر اثرات:
نیند آنا
کمزوری
چکر آنا
متلی
بلڈ پریشر کا کم ہونا
احتیاط:
اچانک بند نہ کریں، دورے یا ذہنی الجھن ہو سکتی ہے
صرف ڈاکٹر کی نگرانی میں استعمال کریں
BACLOFEN(TAB)
Baclofen Tablet – Urdu and English Information:
English:
Medicine Name: Baclofen
Form: Tablet
Strengths: 5 mg, 10 mg, 25 mg (commonly)
Used For:
Muscle spasms
Spasticity caused by conditions like multiple sclerosis, spinal cord injury, etc.
How it Works:
Baclofen is a muscle relaxant. It works on the central nervous system (brain and spinal cord) to reduce stiffness and muscle spasms.
Common Side Effects:
Drowsiness
Dizziness
Weakness
Nausea
Headache
اردو:
دوائی کا نام: بیکلوزین (Baclofen)
شکل: گولی (Tablet)
طاقت: 5 ملی گرام، 10 ملی گرام، 25 ملی گرام
استعمالات:
پٹھوں کی کھچاؤ یا جھٹکے
اعصابی بیماریوں جیسے کہ ملٹی پل اسکلروسیز یا ریڑھ کی ہڈی کی چوٹ کی وجہ سے ہونے والے پٹھوں کی سختی
یہ کیسے کام کرتی ہے:
بیکلوزین دماغ اور ریڑھ کی ہڈی پر اثر ڈال کر پٹھوں کو ڈھیلا کرتی ہے، جس سے سختی اور کھچاؤ میں کمی آتی ہے۔
عام مضر اثرات:
نیند کا زیادہ آنا
چکر آنا
کمزوری
متلی
سر درد
BACLOFEN LOCAL AND INTERNATIONAL BRAND:
Here are some local (Pakistan) and international brand names of Baclofen:
🇵🇰 Local Brands (Pakistan):
- Baclor – Getz Pharma
- Lioresal – Novartis (also considered international)
- Baclomol – Searle
- Bacloran – Hilton Pharma
- Bacfen – Sami Pharma
- Myobac – Global Pharma
🌍 International Brands:
- Lioresal – Novartis (global brand, widely used)
- Kemstro – U.S. (oral disintegrating tablets)
- Gablofen – U.S. (injectable form)
- Ozobax – U.S. (oral solution)
- Baclosan – India (Intas)
- Baclofen-Ratiopharm – Germany
- Baclofen Teva – Europe
- Baclofen Mylan – Australia/Canada
BACLOFEN (TAB) AND (INJ) PICTURE:
Here are clear images of baclofen injection vials (ampoules used intrathecally, e.g. Lioresal Intrathecal) and oral baclofen tablets (commonly 5 mg, 10 mg, 20 mg):
💉 Baclofen Injection
Typically a preservative‑free, latex‑free sterile solution, available in varying concentrations like 0.05 mg/mL, 0.5 mg/mL, up to 2 mg/mL, and supplied in small vials or ampoules .
Administered directly into the intrathecal space (around the spinal cord), often used with test dosing before long‑term pump implantation. It provides high spinal fluid levels with much lower blood levels than oral dosing .
Cleveland Clinic notes it “relaxes your muscles, which reduces muscle stiffness” and is for severe spasms .
💊 Baclofen Tablets
Round, white tablets, usually 5 mg, 10 mg, or 20 mg; imprint codes (e.g., “B 10”, “U‑S BAC 20”) vary by manufacturer .
Example: 10 mg tablets are white, round, often imprinted “024” or similar .
Used orally to treat spasticity from conditions like multiple sclerosis or spinal cord injury, acting as a skeletal muscle relaxant .
Quick Comparison Table
Form Appearance Route Common Use
Injection Clear sterile vial, ampoule Intrathecal (spinal) Severe spasticity not responding to oral baclofen
Tablet White, round/oval tablet Oral General muscle spasms in MS, spinal cord injury
🔍 Important Points
Injection vs Tablet: Intrathecal injection targets the spinal fluid directly—more potent local effect, fewer systemic effects. Oral tablets are easier to take but may cause sedation or dizziness.
Identifying Tablets: Always check imprint, shape, and color if confirming a tablet—multiple codes like B 10, U‐S BAC, 1285, etc. are used .
Safety & Use: Do not stop suddenly—especially injections—as withdrawal may be dangerous. Side effects: drowsiness, dizziness, nausea .
If you’re confirming a specific vial or tablet in hand, use the label details like dosage strength, vial volume, tablet imprint, and compare to pill identifier tools like Drugs.com. For clinical guidance, always rely on your healthcare provider or pharmacist’s information.
